The easiest way to delete a profile is to use the Profile Management tool in SpyderUtility.

Click on the SpyderUtility then choose Profile Management. The bold profile in the list to left of the Profile Management window is your current display profile.

Select the profile you want to delete and click the ‘Delete...’ button. The currently active monitor profile can not be deleted, select a different profile as active profile first.

You can also click on the ‘Show on Disk’ button, this will take you to your profiles folder on your computer. Now you can use the Finder (Mac) or Windows Explorer (Windows) to choose the profile you want to delete then send it to your Trash then empty your Trash. It might be necessary to reboot your computer at this point.