Though there is overlap, both products serve specific purposes. The 48-patch SpyderCHECKR has a more comprehensive set of color patches. As a result, it offers slightly more subtle corrections. The rigid case makes the 48-patch SpyderCHECKR more convenient for setting up on a tripod or light stand.
The SpyderCHECKR 24 is more portable and fits into smaller shots such as close-up and product photography. SpyderCHECKR 24 is also lower cost so it is ideal for situations where the target might be lost or damaged.